The term MRSA literally means "Selective Androgen Receptor Modulators". The androgens are a class of hormones that serve as ligands which bind to cellular androgen receptors. All anabolic steroids and pro-hormones offer their muscle-building properties through this binding to the androgen receptor.
A drug that can either block or stimulate the same nuclear hormone receptor in different conditions is called a selective receptor modulator. If one can block or stimulate a tissue receptor in a selective manner, it may be able to mimic the beneficial effects in tissue and, at the same time minimize adverse effects of steroid hormones in other tissues.
MRSA are developed and studied for 1998. They were originally sought for those requiring hormone replacement therapy and those who fight against various diseases such as cancer or osteoporosis.
Pharmaceutical companies are studying SARMS as a breakthrough in the medical industry because of their ability to stimulate the receptor tissue in a selective manner and to reduce or eliminate the undesirable effect of secondary sides.
MRSA and Medicine
The steroids are usually prescribed medicine for two distinct reasons:
- The muscle diseases ranging from osteoporosis to cancer
- replacement therapy hormone
The medicine then thought that it is possible to stimulate a tissue receptor selectively (eg selective tissue to bone and muscle), it is possible to mimic the beneficial effects of activation of androgen and at the same time, minimize adverse effects natural or synthetic steroid hormones in other tissues.
The side effects of MRSA
As previously indicated, problems with anabolic steroid or testosterone replacement therapy come from their adverse side effects or pharmacokinetic properties.
In particular many important more or less side effects can occur, such as:
- Potential stimulation of prostate cancer
- Hair growth or body
- Gynecomastia (male breast development)
- High blood pressure
- Liver toxicity
- Cholesterol imbalance
- The left ventricular hypertrophy (enlargement of the heart)
- Stopping your own testosterone production
How to avoid these side effects?
Stimulate the androgen receptor in muscle and bone tissue can prevent most, if not all of the harsh side effects indicated above.
For this specificity makes these modulators capable of selectively causing muscle growth receptors, that research turned to MRSA. Because they offer the potential to exploit the benefits of anabolic supplements while minimizing side effects. They also have the potential advantages of oral administration, testosterone and certain steroids do not offer.
So pharmaceutical companies are currently investigating whether MRSA can really be an alternative to prescribed steroids.
Global pharmaceutical companies are testing several types of MRSA. There are in fact several hundred, but there are two main currently available and what are the most used by athletes, fitness enthusiasts and bodybuilders. It is the ostarine (MK-2866) and of the andarine (S-4).
MRSA in sports and bodybuilding
Many sports are concerned by these findings. In particular all athletes who, for their training or to improve performance, use steroids. So the bodybuilders, but also the fitness practitioners, and many athletes. MRSA can actually be used in conjunction or in place of anabolic for the following uses:
- Lean muscle growth
- Prevent muscle loss during weight loss
- Rehabilitation of injuries
- Use of the PCT after anabolic.
Moreover, the benefits for them are numerous. Catches are oral (so no injections required with hygiene-related health risks), effects similar to those of testosterone (strength gain, increased libido, loss of fat), no conversion dihydrotestosterone, No estrogen conversion, no hepatic toxicity, No detection of risks in case of doping control.
If the disadvantages are largely eliminated what about the benefits, particularly in building muscle?
The first generations of MRSA have shown that they induce modest gains in lean body mass in healthy subjects, thus quite far from what was happening with testosterone or anabolic steroids. For example, one study found that MRSA produce a gain in 1,0 1,5 kg lean mass after four to six weeks whereas traditional anabolic produced on the same period in 5 7 kg lean mass.
But new generations of MRSA can be considerably more powerful than the older.
The two main MRSA used are theostarine and andarine. The first is the most powerful of MRSA. It is very effective in maintaining lean body mass. This is often called MRSA S1. It was developed early in the search but now longer subject to further developments.
THE'ostarine exerts its effects mainly on muscle tissue. It is strongly recommended for all medical treatments against muscle wasting diseases but it is also enjoyed by all bodybuilders as regards the muscle building. On more than 600 people tested in clinical trials, 160 of them have achieved the goal of increased total lean mass and the objective of increasing muscle mass. Theostarine therefore seems to be the ideal product to increase lean body mass of athletes. The only downside seems to be the time needed to win this lean body mass because it is superior to conventional anabolic. However the advantage of not having any side effects is without doubt much higher.
THE'andarine, Meanwhile, is appointed S4. This MRSA as a primary property reduce body fatAt the same time it will allow forincrease muscle mass. The effects of S4 are often compared to those of Winstrol but without the side effects such as hair loss. andarine will help you get a lean look, hard and dry. It gives you the strength and endurance. It may very well be coupled with ostarine to further enhance its effects. Like all MRSA, it provides less anabolic androgenic steroids that real, but the effects are very similar.