IGF-1 is the abbreviation of Insulin-like Growth Factor 1 which can result in 1 like growth factor in insulin. Also known under the name of somatomedin CThis hormone is produced mainly by the liver through stimulation of the latter by the Growth Hormone (GH) deficiency. It is released into the blood circulation.
Indeed, theIGF 1 is a growth factor, but we must have the good rate, too low or too high levels can cause problems. IGF plays 1 a lever for growth children, and clinical studies have shown that milk proteins have an important effect on plasma IGF 1.
It is even considered that the evolution of the size of the "young" rising in many countries, is causing a large consumption of milk and dairy products, due to the protein contained.
Regular physical activity or sport practiced intensively reduces the production by the body of IGF 1 and increases the fixing thereof in the blood (through IGF BP), this allows a limitation of the loss of bone density that occurs for all, with age.
Effects of doping with IGF-1
Insulin-like Growth Factor 1, somatomedin. This product is expected to produce the same effects as insulin, as qu'anabolisant, is this the case? Let's go a little further in detail ...
For years everyone speaks in gyms, clubs and muscu magazines on bodybuilding, IGF-1 hormone.
IGF has an identical growth factor insulinIt is also called somatomedin C. Its role is extremely important in the growth of young children, and for adults, it plays an anabolic role.
It is the growth hormone which determines its actuation. This growth hormone triggers the action of the liver that produces hormones which are responsible for muscle growth. One such hormone is IGF-1,
IGF-1 has a much more direct action as growth hormone itself. It is therefore very easy to understand the interest that can have all bodybuilding practitioners and other "cast leveler"
What are the effects of IGF-1 hormone for athletes who practice strength training?
- It causes bone and muscle growth
- It has an anabolic role, that is to say that it is a substance that increases anabolism, in other words the processing of nutrients in living tissue.
- The hormone IGF1 also brings a real improvement in the recovery and also of healing, it also reduces body fat.
It is still important to note that growth hormone makes you fat throughout the body and therefore all muscles. It is useful and necessary to draw attention to the fact that the body may be deformed. It is quite easy and easy for an expert, to identify an athlete who consumes this type of product.
The human growth hormone IGF 1 has many positive effects. It causes muscle building by increasing cells (hyperplasia), while on the contrary, anabolic steroids will simply increase the size of existing muscle cells.
This means that even after stopping his grip, you will continue to progress.
Few studies have been conducted on against IGF LR3 (in contrast to IGF 1) yet is known to have a power to 2 3 times that IGF 1 standard due to a longer half life.
IGF 1 is rarely used because its life is very short at least 10 more minutes. His substitute theIGF 1 LR3 (Modified version of IGF-1, which is not naturally produced by the body) is widely preferred, the duration of use of up to several hours. Hence its decision are less frequent and in smaller amounts in lyophilized or already reconstituted form.
Its dosage goes to 20 120 mcg / day. The results are visible quickly enough. The duration of the cure ranges from 4 50 weeks to days. The ideal is taken by intramuscular injection just after training.
A study of male subjects who were injected daily over a period of 6 weeks (with either HGH alone, IGF-alone or IGF-1 1 + HGH together) shows the increase in lean body mass, increased strength and decreased fat mass.
PEG-MGF (growth factor)
A scientific report shows the doping potential of this product. An initial study showed that a single injection of mouse muscle allowed growth 25% thereof, in only 3 weeks.
The side effects of IGF-1
Hypoglycemia: Hypoglycemia can cause dizziness and vertigo. This can be compensated by a balanced diet and carbohydrate intake soon after the injections
Water Retention: some users have expressed the characteristic of water retention. The excess is fixed in the tissues, the body stores more water than it eliminates.
Supply at a IGF-1 cure
IGF-1 peptides are not influenced by food. So there is no regime of coercion or dietary modification to have.
The only "rules" for IGF-1 peptides are oftry to make the injections as soon as possible after trainingAnd if possible into a muscle so the localized muscle building can start occurring immediately. However, if you can not follow these rules do not worry as the long half-life of both peptides means that your injections will still be carried through the blood system and find the receptor sites in the muscles to perform their anabolic effects.
As the primary role of IGF-1 and PEG-MGF is create new muscle cellsThe best diet is a diet high in protein, preferably taken around workouts.
The most important time for the consumption of these proteins, preferably in liquid form amino acids such as BCAA, immediately just before the meeting and also during your workout.
Indeed, a very logical decision protein after training does not contribute to muscle protein synthesis, but the synthesis of total protein in the body, and the consumption of amino acids during a session training leads directly to muscle protein synthesis due to the circulation of the blood faster due to the force produced, thus causing more effective delivery of amino acids to the muscles directly.
There are also variations, with theIGF-1 DES. Its efficacy is 10 times that of normal IGF-1.
IGF-1, in its natural version (endogenous), is composed of amino acids 70. The DES (1,3) IGF-1 has undergone a change in its "sequence", 3 the last amino acids (N-terminal tri-peptide end) have been removed.
With this change, IGF-1 OF presents no blocking due to a dependence on the binding protein that allows it to flow. The circulating IGF-1 DES is indeed free and available throughout the bloodstream waiting to find a receiver.
During physical exertion, a combustion occurs in the muscle with oxygen and sugar. This creates ADP (adenosine diphosphate) and then the lactic acid.
The accumulation of lactic acid in the muscles causes the burning sensation see higher dose cramps. Furthermore this prevents acid receptors function correctly. Some anabolic and anti-catabolic therefore will not find their receiver and will therefore not act. This can happen with IGF-1, but not IGF-1 DES which is free to the receiver.
IGF-DES is 1 100% bio available (because it is not bound to the receptors), it is 10 times anabolic IGF-1 created by the body and it has the advantage of be active even when the lactic acid appears in muscle tissue.
So many will regret that his life activity only lasts a few minutes.